NDM-1 In The United States

Currently, NDM-1 is not widespread in the United States, but this newsfeed is set to constantly update with the latest news and information about any developments in the United States.

It is fastest way to keep up with the latest developments on NDM-1, particularly any news from the Centers for Disease Control or announcements by the Surgeon General.

• Nature publishes details of bird flu strain that could spread among people - Publication of bird flu study was delayed after warnings that the information could be exploited by terroristsControversial research on a hybrid strain of bird flu that could potentially spread between humans was published on Wednesday in Nature after security restrictions on the work were lifted.Scientists created the virus by merging a mutated strain of bird flu with the "swine flu" virus that sparked a human pandemic in 2009. The hybrid strain spread easily between ferrets – the best proxy that flu researchers have for people – but was not lethal and could be controlled with antiviral drugs and bird flu vaccines.The work by Yoshihiro Kawaoka at the University of Wisconsin-Madison was submitted last year to the journal, but was delayed after the US government's biosecurity advisers s...

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• [A(H1N1)v cases of the 2009/2010 and 2010/2011 influenza seasons in the Medical and Health Sciences Centre of Debrecen University]. - Conclusion: It is an important task to protect oncohematological and organ transplant patients. Orv. Hetil., 2012, 153, 649-654. PMID: 22543220 [PubMed - in process] (Source: Orvosi Hetilap)
• Human Infections with Novel Reassortant Influenza A(H3N2)v Viruses, United States, 2011. - Authors: Lindstrom S, Garten R, Balish A, Shu B, Emery S, Berman L, Barnes N, Sleeman K, Gubareva L, Villanueva J, Klimov A Abstract During July-December 2011, a variant virus, influenza A(H3N2)v, caused 12 human cases of influenza. The virus contained genes originating from swine, avian, and human viruses, including the M gene from influenza A(H1N1)pdm09 virus. Influenza A(H3N2)v viruses were antigenically distinct from seasonal influenza viruses and similar to proposed vaccine virus A/Minnesota/11/2010. PMID: 22516540 [PubMed - in process] (Source: Emerging Infectious Diseases)
• Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication - Conclusions  Retinoic acid promoted ciliogenesis, whereas epidermal growth factor controlled the thickness of the pseudoepithelium. The optimal concentrations for differentiated swine cell cultures were 1·5 ng/ml epidermal growth factor and 100 nm retinoic acid. Influenza A viruses infected and productively replicated in these cultures in the absence of exogenous trypsin, suggesting that the cultures express a protease capable of activating influenza virus hemagglutinin. Differences in virus infection and replication characteristics found previously in pigs in vivo were recapitulated in the swine cultures. This system could be a useful tool for a range of applications, including investigating influenza virus species specificity, defining cell tropism of influenza viruses in the swin...
• Biosecurity aspects and pathogen inactivation in acidified high risk animal by-products. - Authors: Vinnerås B, Samuelson A, Emmoth E, Nyberg KA, Albihn A Abstract The aim of the study was to investigate the effects of formic acid addition to ground high risk animal by-products (ABP 1) in terms of stabilization and pathogen inactivation and to evaluate the biosecurity risk connected with the ABP 1 based combustion fuel Biomal. Laboratory studies were performed on the persistence of Salmonella Typhimurium, Bacillus cereus spores, porcine herpes virus, avian influenza virus, bovine viral diarrhea virus, equine rhinitis A virus and porcine parvovirus in Biomal at different storage times. It was shown that Salmonella and enveloped viruses were inactivated within 1 day (24 h). Bacillus cereus spores were not reduced during 147 days and the non-enveloped virus porcine parvovi...

NDM-1 In Europe and the UK

• FDA Approves First Quadrivalent Vaccine to Prevent Seasonal Influenza - FluMist Quadrivalent, a vaccine to prevent seasonal influenza in people ages 2 years through 49 years, has been approved today by the U.S. Food and Drug Administration. FluMist Quadrivalent is the first influenza vaccine to contain four strains of the influenza virus, two influenza A strains and two influenza B strains.
• First U.S. Cell-based Flu Vaccine Plant Set for Dedication - The first U.S. facility to use a faster and more flexible technology to make influenza vaccine was dedicated today, as part of an initiative that could provide vaccine supplies sooner in an influenza pandemic. The plant in Holly Springs, N.C., can create vaccine using cultured animal cells instead of the conventional process of using fertilized eggs.
• CDC Confirms Two Human Infections with Novel Influenza Viruses - CDC has confirmed two cases of human infection with two different novel influenza A viruses in different states. Both patients have fully recovered.
• FDA Updated Communication on Use of Jet Injectors with Inactivated Influenza Vaccines - The Food and Drug Administration (FDA) is recommending that health care professionals use a sterile needle and syringe to administer inactivated influenza vaccines.
• CDC Issues Initial 2011-2012 Seasonal “FluView” Report: Current Activity is Low; Outlook for Vaccine is Good - The Centers for Disease Control and Prevention released the initial “FluView” report for the U.S. 2011–2012 flu season with the message that flu activity is currently low, making this the perfect time to get vaccinated. There should be lots of vaccine available, because the supply is projected to set a U.S. record.

Antibiotic Resistance

• FDA Approves First Quadrivalent Vaccine to Prevent Seasonal Influenza - FluMist Quadrivalent, a vaccine to prevent seasonal influenza in people ages 2 years through 49 years, has been approved today by the U.S. Food and Drug Administration. FluMist Quadrivalent is the first influenza vaccine to contain four strains of the influenza virus, two influenza A strains and two influenza B strains.
• First U.S. Cell-based Flu Vaccine Plant Set for Dedication - The first U.S. facility to use a faster and more flexible technology to make influenza vaccine was dedicated today, as part of an initiative that could provide vaccine supplies sooner in an influenza pandemic. The plant in Holly Springs, N.C., can create vaccine using cultured animal cells instead of the conventional process of using fertilized eggs.
• CDC Confirms Two Human Infections with Novel Influenza Viruses - CDC has confirmed two cases of human infection with two different novel influenza A viruses in different states. Both patients have fully recovered.
• FDA Updated Communication on Use of Jet Injectors with Inactivated Influenza Vaccines - The Food and Drug Administration (FDA) is recommending that health care professionals use a sterile needle and syringe to administer inactivated influenza vaccines.
• CDC Issues Initial 2011-2012 Seasonal “FluView” Report: Current Activity is Low; Outlook for Vaccine is Good - The Centers for Disease Control and Prevention released the initial “FluView” report for the U.S. 2011–2012 flu season with the message that flu activity is currently low, making this the perfect time to get vaccinated. There should be lots of vaccine available, because the supply is projected to set a U.S. record.

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